Resident Evil: Afterlife (2010) marks the fourth installment in the action-horror film saga inspired by Capcom’s legendary video game franchise. Packed with explosive action, terrifying creatures, and iconic heroes, this chapter continues Alice’s journey through a world overrun by the T-virus. For fans of the franchise, getting to know the main Resident Evil 4 characters is essential to fully appreciate the narrative and the chaos they endure.
Oh, and by the way—you can stream the movie on Prime Video now and get 30 days free trial.

Alice Abernathy (Milla Jovovich)
Alice is the fearless heroine of the entire movie series. Formerly a security officer for the Umbrella Corporation, she’s been genetically modified by the T-virus, gaining superhuman strength, speed, and agility. In Resident Evil 4: Afterlife, Alice continues her mission to destroy Umbrella and protect the remaining human survivors. As one of the most iconic Resident Evil 4 characters, she’s relentless, tactical, and emotionally driven.

Claire Redfield (Ali Larter)
Claire returns as a strong, battle-hardened survivor and a natural leader. After losing her memory due to Umbrella’s mind-control devices, she reunites with Alice and slowly regains her identity. Claire is one of the central 4 characters that bring emotional weight and grit to the group’s dynamic. Her chemistry with Alice and protective instincts make her indispensable.

Chris Redfield (Wentworth Miller)
Making his film debut, Chris Redfield is Claire’s brother and a skilled combat veteran. He’s introduced as a prisoner in a high-security cell in a post-apocalyptic Los Angeles prison. Once freed, he becomes a key player in the fight against the undead and Umbrella. As one of the most anticipated Resident Evil 4 characters, his arrival thrilled fans of the video games.

Albert Wesker (Shawn Roberts)
Wesker is the sinister mastermind of Umbrella and the main villain in Resident Evil 4: Afterlife. Enhanced by the T-virus, he’s nearly unstoppable. Wesker’s cold demeanor and ruthless tactics make him one of the most dangerous characters in the film, and his final showdown with Alice is unforgettable.

Luther West (Boris Kodjoe)
Luther is a former basketball star turned survival leader. He brings optimism, courage, and heart to the group. Among the Resident Evil 4 characters, Luther’s role stands out for his moral strength and his desire to protect others, even when faced with impossible odds.

Bennett Sinclair (Kim Coates)
Bennett is a shady film producer who survives the apocalypse only to prove that selfishness doesn’t fade in the face of danger. Opportunistic and manipulative, his presence brings tension and conflict to the group dynamic—often putting everyone at risk.

Angel Ortiz (Sergio Peris-Mencheta)
Angel is a soft-spoken but resourceful survivor. As a mechanic, he provides essential skills to the group, helping them build and fix things needed for survival. While not as prominent as others, Angel’s quiet loyalty adds depth to the lineup of Resident Evil 4 characters.

Crystal Waters (Kacey Barnfield)
Crystal, a young aspiring actress and former swim champion, brings a mix of innocence and bravery. Her swimming skills come in handy during escape sequences, proving that even the seemingly unprepared characters have a role to play in survival.

Kim Yong (Norman Yeung)
Kim is the former assistant to Bennett and brings a tech-savvy presence to the group. His analytical mind adds a layer of intelligence, even as he deals with the emotional toll of betrayal and survival.

K-Mart (Spencer Locke)
K-Mart, a returning survivor from earlier films, continues to grow emotionally and physically as she supports Alice and Claire. Though her screen time is limited in this installment, her presence maintains continuity and strengthens the bond between several Resident Evil 4 characters.

Jill Valentine (Sienna Guillory)
Jill makes a surprise post-credits appearance, this time as an antagonist under Umbrella’s mind control. Her transition from hero to villain foreshadows major developments in upcoming films. Jill is one of the most iconic characters, setting the stage for future drama.

The Axeman (Ray Olubowale)
Straight out of the video games, this terrifying monster—also known as The Executioner—wields a massive axe and delivers some of the film’s most suspenseful action. As a non-human addition, his brutal presence adds a horror-game vibe that fans love.
Why Fans Still Love Resident Evil 4: Afterlife
Among all the films in the series, “Afterlife” stands out for its bold use of 3D effects, strong character arcs, and the introduction of fan-favorite Resident Evil 4 characters like Chris Redfield and The Axeman. The prison setting, aircraft carrier finale, and slow-motion combat scenes all help deliver a cinematic experience that’s both thrilling and nostalgic for longtime fans.
Stream Resident Evil 4: Afterlife on Prime Video
Ready to revisit this action-horror classic or watch it for the first time? Resident Evil: Afterlife is available now on Prime Video. Whether you’re into gory zombie battles or tight-knit survival stories, it’s a must-watch.
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